Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Uncategorized, Vector & Virus, Western Blot

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.
Posted by Seth

Ikaros family zinc finger 1 (IKZF1) is a transcription factor with an important role in controlling the proliferation of hematopoietic and function, particularly lymphoid cell differentiation. It was previously demonstrated that a variety of mechanisms and Ikaros expression patterns associated with various cancers. We hypothesize that aberrant methylation (hypomethylation) of the promoter region IKZF1 probably one of the causes of acute lymphoblastic leukemia B-cells (B-ALL). In the B-ALL patients, increased expression of this gene is a potential cause of B cell differentiation arrest and proliferation induction.

Therefore, as more than 90% of patients with ALL is <15 years, we investigated the promoter methylation patterns IKZF1 in childhood B-ALL.Twenty five newly diagnosed cases of B-ALL included (all younger than 15 years). In addition, we selected 25 children age and sex-matched healthy control group. We collected blood samples in EDTA-containing tubes and lymphocytes were isolated from whole blood using Ficoll 1,077 Lymphosep. Next, we extracted genomic DNA by the method of phenol / chloroform.

Two micrograms of DNA per sample is treated with sodium bisulfite using bisulfite EpiTect Kit, followed by an assessment of DNA methylation by polymerase chain reaction (PCR) analysis of data DNA.Our bisulfite-modified genomic highlighted hypomethylated status of promoter IKZF1 in ALL cases (96% of cases unmethylated).

In contrast, the control group sample partially methylated (68%). This study shows the pattern of the promoter region IKZF1 hypomethylated in childhood B-ALL, which may underlie aberrant patterns of expression of Ikaros previously associated with this malignancy.

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.
An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.

HDAC6-selective inhibitor synergistically enhances the anticancer activity immunomodulatory drugs in multiple myeloma.

Non-selective histone deacetylase (HDAC) inhibitors have therapeutic effects, but exhibit the dose-limiting toxicities in patients with multiple myeloma (MM). This study examined the interaction between inhibitors of HDAC6, A452, and immunomodulatory drugs (IMiDs) of the dexamethasone (Dex) -sensitive MM cells and resistant compared to current clinically proven HDAC6 inhibitor, ACY-1215.

This suggests that the combination of HDAC6-selective inhibitor, A452, with one of the IMiDs tested (lenalidomide or pomalidomide) causes a synergistic inhibition of cell growth, a decrease in MM cell viability and increased levels of apoptosis. In addition, the enhanced cell death associated with inactivation of AKT and extracellular signal-regulated kinase (ERK) 1/2. Of note, the A452 in combination with synergistically induced MM cytotoxicity IMiDs without changing cereblon expression and thus, downregulation synergistic zinc finger family IKAROS (IKZF) 1/3, c-Myc and interferon regulatory factor 4 (IRF4).

Furthermore, combined with A452 and IMiDs treatment synergistically induced upregulation of PD-L1. More importantly, this combination treatment is effective in Dex-resistant MM cells. Overall, the findings of this study show that the A452 is more effective as an anticancer agent from ACY-1215. Taken together, these findings suggest that the combination of HDAC6-selective inhibitor, A452, and IMiDs may prove useful in the treatment of patients with male patients aged 11 years MM.

An with the removal IKZF1 (Ikaros family zinc finger 1) and positive Breakpoint Regional cluster-C-Abelson oncogene 1 (BCR-ABL1) acute lymphoblastic leukemia developed mucositis, gastrointestinal toxicity, hepatotoxicity, myelosuppression, and severe dermatologic toxicities during the first and second courses of high-dose methotrexate. patients recover fully after treatment.

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

RDR-TACR1-Hu-48Tests 48 Tests
EUR 500

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

RDR-TACR1-Hu-96Tests 96 Tests
EUR 692

Tachykinin Receptor 1 (TACR1) Antibody

20-abx115974
  • EUR 732.00
  • EUR 398.00
  • 150 ul
  • 50 ul

Tachykinin Receptor 1 (TACR1) Antibody

20-abx121769
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Tachykinin Receptor 1 (TACR1) Antibody

20-abx110235
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Tachykinin Receptor 1 (TACR1) Antibody

20-abx004264
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tachykinin Receptor 1 (TACR1) Antibody

20-abx015349
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Tachykinin Receptor 1 (TACR1) Antibody

abx431635-200ul 200 ul
EUR 384

Tachykinin Receptor 1 (TACR1) Antibody

20-abx178530
  • EUR 1107.00
  • EUR 537.00
  • 1 mg
  • 200 ug

Tachykinin Receptor 1 (TACR1) Antibody

20-abx174707
  • EUR 787.00
  • EUR 411.00
  • 1 mg
  • 200 ug

Tachykinin Receptor 1 (TACR1) Antibody

20-abx328174
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Tachykinin Receptor 1 (TACR1) Antibody Pair

abx117530-1pair5x96wellplates 1 pair (5x96 well plates)
EUR 1010

Neurokinin Receptor (393 -407), rat

5-01595 4 x 5mg Ask for price

Neurokinin Receptor (393 407) Peptide

20-abx265658
  • EUR 551.00
  • EUR 926.00
  • EUR 398.00
  • 10 mg
  • 25 mg
  • 5 mg

Human Tachykinin Receptor 1 (TACR1) Protein

20-abx655187
  • EUR 885.00
  • EUR 328.00
  • EUR 2834.00
  • EUR 1052.00
  • EUR 606.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

SEA392Hu-10x96wellstestplate 10x96-wells test plate
EUR 4273.35
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tachykinin Receptor 1 (TACR1) in Tissue homogenates, cell lysates and other biological fluids.

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

SEA392Hu-1x48wellstestplate 1x48-wells test plate
EUR 439.57
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tachykinin Receptor 1 (TACR1) in Tissue homogenates, cell lysates and other biological fluids.

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

SEA392Hu-1x96wellstestplate 1x96-wells test plate
EUR 585.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tachykinin Receptor 1 (TACR1) in Tissue homogenates, cell lysates and other biological fluids.

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

SEA392Hu-5x96wellstestplate 5x96-wells test plate
EUR 2332.95
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Tachykinin Receptor 1 (TACR1) in Tissue homogenates, cell lysates and other biological fluids.

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

4-SEA392Hu
  • EUR 4324.00
  • EUR 2283.00
  • EUR 586.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Tachykinin Receptor 1 (TACR1) in samples from Tissue homogenates, cell lysates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Tachykinin Receptor 1 ELISA Kit (TACR1)

RK02352 96 Tests
EUR 521

Pig Tachykinin Receptor 1 (TACR1) ELISA Kit

abx361068-96tests 96 tests
EUR 825

Rabbit Tachykinin Receptor 1 (TACR1) ELISA Kit

abx362601-96tests 96 tests
EUR 825

Chicken Tachykinin Receptor 1 (TACR1) ELISA Kit

abx356586-96tests 96 tests
EUR 825

Monkey Tachykinin Receptor 1 (TACR1) ELISA Kit

abx359122-96tests 96 tests
EUR 825

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

20-abx153216
  • EUR 6642.00
  • EUR 3542.00
  • EUR 825.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Tachykinin Receptor 1 (TACR1) CLIA Kit

abx196084-96tests 96 tests
EUR 825

Mouse Tachykinin Receptor 1 (TACR1) CLIA Kit

abx196085-96tests 96 tests
EUR 825

Rat Tachykinin Receptor 1 (TACR1) CLIA Kit

abx196086-96tests 96 tests
EUR 825

Human Tachykinin Receptor 1 (TACR1) ELISA Kit

abx253237-96tests 96 tests
EUR 707

Mouse Tachykinin Receptor 1 (TACR1) ELISA Kit

abx254443-96tests 96 tests
EUR 707

Rat Tachykinin Receptor 1 (TACR1) ELISA Kit

abx256029-96tests 96 tests
EUR 707

Mouse Tachykinin Receptor 1 (TACR1) ELISA Kit

abx257664-96tests 96 tests
EUR 637

Human Tachykinin Receptor 1 (TACR1) CLIA Kit

20-abx491437
  • EUR 7973.00
  • EUR 4246.00
  • EUR 981.00
  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Rat TACR1(Tachykinin Receptor 1) ELISA Kit

ER1360 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Rattus;Sensitivity: 75pg/ml

Rat Tachykinin Receptor 1(TACR1)ELISA Kit

QY-E10022 96T
EUR 361

Mouse Tachykinin Receptor 1(TACR1)ELISA Kit

QY-E21424 96T
EUR 361

Human Tachykinin Receptor 1(TACR1)ELISA Kit

QY-E01373 96T
EUR 361

Human TACR1(Tachykinin Receptor 1) ELISA Kit

EH3842 96T
EUR 524.1
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.188 ng/ml

ELISA kit for Mouse TACR1 (Tachykinin Receptor 1)

E-EL-M1111 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Mouse TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Human TACR1 (Tachykinin Receptor 1)

E-CL-H1200 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Human TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

CLIA kit for Mouse TACR1 (Tachykinin Receptor 1)

E-CL-M0627 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Mouse TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human TACR1 (Tachykinin Receptor 1)

ELK1512 1 plate of 96 wells
EUR 432
Description: A sandwich ELISA kit for detection of Tachykinin Receptor 1 from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

CLIA kit for Rat TACR1 (Tachykinin Receptor 1)

E-CL-R0625 1 plate of 96 wells
EUR 584
Description: A sandwich CLIA kit for quantitative measurement of Rat TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Human TACR1 (Tachykinin Receptor 1)

E-EL-H1961 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Human TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

ELISA kit for Rat TACR1 (Tachykinin Receptor 1)

E-EL-R0936 1 plate of 96 wells
EUR 534
Description: A sandwich ELISA kit for quantitative measurement of Rat TACR1 (Tachykinin Receptor 1) in samples from Serum, Plasma, Cell supernatant

TACR1 ELISA Kit| Rat Tachykinin Receptor 1 ELISA Kit

EF018058 96 Tests
EUR 689

TACR1 ELISA Kit| Mouse Tachykinin Receptor 1 ELISA Kit

EF013913 96 Tests
EUR 689

Anti-Neurokinin 1 Receptor/TACR1 Antibody

PA1684 100ug/vial
EUR 294

Anti-Neurokinin 1 Receptor/TACR1 Antibody

PB9446 100ug/vial
EUR 294

Anti-TACR1 antibody

STJ27535 100 µl
EUR 277
Description: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P.

Anti-TACR1 antibody

STJ71169 100 µg
EUR 359

Tachykinin Receptor 1 Antibody (Biotin)

20-abx105944
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Tachykinin Receptor 1 Antibody (FITC)

20-abx107359
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Tachykinin Receptor 1 Antibody (HRP)

20-abx108780
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Tachykinin Receptor 3 Antibody

20-abx141264
  • EUR 356.00
  • EUR 537.00
  • EUR 217.00
  • 100 ul
  • 200 ul
  • 30 ul

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Tachykinin Receptor 1 Blocking Peptide

20-abx161479
  • EUR 606.00
  • EUR 1428.00
  • 1 mg
  • 5 mg

pCR4-TOPO-TACR1 Plasmid

PVTB00150-1 2 ug
EUR 356

Anti-TNF Receptor 1 Antibody

A00294-1 200ug
EUR 522
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Tachykinin Receptor 2 (TACR2) Antibody

20-abx130253
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Tachykinin Receptor 3 (TACR3) Antibody

20-abx320070
  • EUR 300.00
  • EUR 244.00
  • 100 ul
  • 50 ul

Tachykinin Receptor 2 (TACR2) Antibody

20-abx339430
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Tachykinin Receptor 2 (TACR2) Antibody

20-abx102297
  • EUR 398.00
  • EUR 133.00
  • EUR 1107.00
  • EUR 537.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Tachykinin Receptor 3 (TACR3) Antibody

20-abx006440
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tachykinin Receptor 2 (TACR2) Antibody

20-abx007341
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Tachykinin Receptor 3 (TACR3) Antibody

abx027890-400ul 400 ul
EUR 523

Tachykinin Receptor 3 (TACR3) Antibody

abx027890-80l 80 µl
EUR 286

Tachykinin Receptor 3 (TACR3) Antibody

abx411977-01mg 0.1 mg
EUR 509

Tachykinin Receptor 2 (TACR2) Antibody

abx430612-200ul 200 ul
EUR 286

Tachykinin Receptor 2 (TACR2) Antibody

abx238471-100ug 100 ug
EUR 551

Tachykinin Receptor 3 (TACR3) Antibody

abx238472-100ug 100 ug
EUR 551

Tachykinin Receptor 2 (TACR2) Antibody

20-abx211186
  • EUR 411.00
  • EUR 300.00
  • 100 ul
  • 50 ul

Tachykinin Receptor 2 (TACR2) Antibody

20-abx178531
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug

Tachykinin Receptor 2 (TACR2) Antibody

20-abx174708
  • EUR 787.00
  • EUR 411.00
  • 1 mg
  • 200 ug

Tachykinin Receptor 2 (TACR2) Antibody

20-abx324327
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Polyclonal Goat Anti-TACR1 Antibody

APR12189G 0.1 mg
EUR 484
Description: A polyclonal antibody raised in Goat that recognizes and binds to Human Goat Anti-TACR1 . This antibody is tested and proven to work in the following applications:

TACR1 Antibody

1-CSB-PA050201
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against TACR1. Recognizes TACR1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: WB, IF, ELISA;WB:1/500-1/2000.IF:1/200-1/1000.ELISA:1/5000

TACR1 Antibody

1-CSB-PA09674A0Rb
  • EUR 317.00
  • EUR 335.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against TACR1. Recognizes TACR1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200

TACR1 Antibody

1-CSB-PA023068GA01HU
  • EUR 597.00
  • EUR 333.00
  • 150ul
  • 50ul
Description: A polyclonal antibody against TACR1. Recognizes TACR1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB

TACR1 Antibody

32916-100ul 100ul
EUR 252

TACR1 Antibody

ABD7405 100 ug
EUR 438

TACR1 Antibody

DF7405 200ul
EUR 304
Description: TACR1 Antibody detects endogenous levels of total TACR1.

TACR1 antibody

70R-20686 50 ul
EUR 435
Description: Rabbit polyclonal TACR1 antibody

Anti-IRF4 (aa393-407) antibody

STJ73607 100 µg
EUR 359

Anti-VEGF Receptor 1/FLT1 Antibody

PA1966-1 100ug/vial
EUR 294

Anti-VEGF Receptor 1/FLT1 Antibody

A00534-1 100ug/vial
EUR 294

Human Substance-P receptor (TACR1)

1-CSB-EP023068HU
  • EUR 380.00
  • EUR 214.00
  • EUR 1309.00
  • EUR 560.00
  • EUR 873.00
  • EUR 262.00
  • 100ug
  • 10ug
  • 1MG
  • 200ug
  • 500ug
  • 50ug
Description: Recombinant Human Substance-P receptor(TACR1),partial expressed in E.coli

Anti-GABA B Receptor 1/GABBR1 Antibody

A07297-1 100ug/vial
EUR 294

Tachykinin angatonist 1

HY-U00392 1mg
EUR 4169

Anti-Fractalkine Receptor Antibody

A00280-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Fractalkine Receptor Antibody (CX3CR1) detection.tested for IHC, WB in Human, Mouse, Rat.

TACR1 Polyclonal Antibody

A54105 100 µg
EUR 570.55
Description: Ask the seller for details

TACR1 Conjugated Antibody

C32916 100ul
EUR 397

Recombinant Tachykinin Receptor 2 (TACR2)

4-RPA618Hu01
  • EUR 560.54
  • EUR 253.00
  • EUR 1827.04
  • EUR 675.68
  • EUR 1251.36
  • EUR 438.00
  • EUR 4417.60
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Human Tachykinin Receptor 2 expressed in: E.coli

Recombinant Tachykinin Receptor 2 (TACR2)

4-RPA618Ra01
  • EUR 530.08
  • EUR 245.00
  • EUR 1712.80
  • EUR 637.60
  • EUR 1175.20
  • EUR 418.00
  • EUR 4132.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
Description: Recombinant Rat Tachykinin Receptor 2 expressed in: E.coli

However, intracranial hemorrhage (ICH) occurred after oral methotrexate at a dose of 25 mg / m2 in maintenance treatment, and he has a neurological sequelae including paralysis hemiplegia.

Related Post

Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Uncategorized, Vector & Virus, Western Blot

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.
Antibodies, Assay Kits, Biology Cells, cDNA, Clia Kits, Culture Cells, Devices, DNA, DNA Templates, DNA Testing, Elisa Kits, Enzymes, Equipments, Exosomes, Gels, Isotypes, Medium & Serums, NATtrol, Panel, Particles, PCR, Pcr Kits, Peptides, Reagents, Recombinant Proteins, Ria Kits, RNA, Test Kits, Uncategorized, Vector & Virus, Western Blot

EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses.

EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses.

Leave A Comment