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An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.

An investigation of methylation pattern changes in the IKZF1 promoter in patients with childhood B-cell acute lymphoblastic leukemia.
Posted by Seth
Ikaros family zinc finger 1 (IKZF1) is a transcription factor with an important role in controlling the proliferation of hematopoietic and function, particularly lymphoid cell differentiation. It was
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Epstein-Barr Virus BART Long Non-coding RNAs Function as Epigenetic Modulators in Nasopharyngeal Carcinoma.

Epstein-Barr Virus BART Long Non-coding RNAs Function as Epigenetic Modulators in Nasopharyngeal Carcinoma.
Posted by Seth
Epstein-Barr virus (EBV) establishes a lifelong latent infection in humans and is associated with several lymphoid and epithelial cancers. In nasopharyngeal carcinoma (NPC), EBV revealed several
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EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses.

EOS, an Ikaros family zinc finger transcription factor, interacts with the HTLV-1 oncoprotein Tax and is downregulated in peripheral blood mononuclear cells of HTLV-1-infected individuals, irrespective of clinical statuses.
Posted by Seth
EOS plays an important role in maintaining the suppressive function of regulatory T cells (Treg), and a set of Tregs induced transformation into T helper-like cells, which are able to secrete
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Development of Label-Free Impedimetric Immunosensors for IKZF1 and IKZF3 Femtomolar Detection for Monitoring Multiple Myeloma Patients Treated with Lenalidomide

Circulating epigenetic biomarkers for detection of recurrent colorectal cancer.
Posted by Seth
Lenalidomide is an immunomodulatory drug (IMiD) is used to treat multiple myeloma (MM) patients. Lenalidomide destroy MM cells to induce ubiquitination and degradation as a result of the Ikaros
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