Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation.

Cells CD4 + T helper cells able to differentiate into several subsets effector perform diverse functions during the adaptive immune response. Each subset differentiation is regulated, largely, by environmental cytokine signaling and subsequent activation of downstream transcription factor network of cell-intrinsic.

Ikaros zinc finger (IkZF) transcription factor known regulator of the development of immune cells, including CD4 + T cell subset Over the past decade, members of the family IkZF also been involved in the differentiation and function of T helper cell subset of individuals, including the T helper 1 (THHHFH ) and regulatory (Treg) cells T. Now, an increasing body of literature suggests that cell-specific cytokine different environment which is responsible for the development of any part results in differential expression IkZF factor of the entire population of T helper.

Interestingly, recent studies have shown that members of IkZF affects T helper differentiation inside the feed-forward mode through the regulatory cytokine-signaling pathways are the same. Here, we review the increasingly important role for IkZF transcription factor in the differentiation of effector CD4 + T helper cell subsets.

Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation.
Ikaros Zinc Finger Transcription Factors: Regulators of Cytokine Signaling Pathways and CD4+ T Helper Cell Differentiation.

Assessing Relevance of Functional Variants in IKAROS Family Zinc Finger Protein 1 (IKZF1) in Cohort Patients With Primary Immunodeficiency.

common variable immunodeficiency (CVID) is the most frequent symptomatic primary immunodeficiency. Patients with CVID are susceptible to recurrent bacterial infections because of a failure of adequate immunoglobulin production. monogenetic defects have been identified in ~ 25% of patients with CVID.

More recently, mutations in IKZF1, encoding zinc-finger transcription factor IKAROS widely expressed in hematopoietic cells, has been associated with CVID like phenotype. Here we describe 11 patients with heterozygous variant IKZF1 of eight different families with autosomal dominant CVID and two siblings with a variant IKZF1 with inflammatory bowel disease (IBD). This study shows that the mutation affects the DNA binding domain IKAROS can disrupt the interaction with the target DNA sequence so as to prevent and localization pericentromeric heterochromatin (HC-PC) protein. Our results also indicate a decrease in localization pericentromeric of IKAROS by overexpression of truncated variants, due to mature stop codon in IKZF1.

We also describe additional variant in TNFSF10, encoding Tumor Necrosis Factor Related Apoptosis Encouraging ligand (TRAIL), also served in the individuals of A. Our Families results show that these variants can disrupt TRAIL-induced apoptosis in the target cell line and forbid the activation of NF by TRAIL and can act as a modifier in Family A
We report a new variant in IKZF1 associated with IKAROS haploinsufficiency in patients with familial immune thrombocytopenia (ITP). IKAROS, encoded by the gene IKZF1, a zinc-finger transcription factor hematopoietic can directly bind to DNA.

Biotin - Gastrin (1-17)

5-00788 4 x 1mg Ask for price

Anti-Sox-17 Antibody

A01665-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Sox-17 Antibody (SOX17) detection. Tested with WB in Human, Mouse.

Gastrin 17 Antigen (HM682)

VAng-Cr3882-1mg 1 mg
EUR 1686
Description: Gastrin 17 Antigen, Host/Source: Synthetic. Matched Pair: HM682 (detection).

Gastrin 17 Antigen (HM683)

VAng-Cr3884-1mg 1 mg
EUR 1686
Description: Gastrin 17 Antigen, Host/Source: Synthetic. Matched Pair: HM683 (detection).

Rabbit Polyclonal antibody Anti-CRBN

Anti-CRBN 50 µg
EUR 349

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Anti-Gastrin antibody

STJ16101195 250 µl
EUR 589

Anti-Gastrin antibody

STJ16101283 50 µl
EUR 635

Anti-Gastrin antibody

STJ16101326 1 mL
EUR 1136

Anti-Gastrin antibody

STJ16101417 50 µl
EUR 635

Anti-Gastrin antibody

STJ16101462 1 mL
EUR 1136

Anti-Gastrin antibody

STJ180107 0.1 ml
EUR 229

Anti-Gastrin antibody

STJ190058 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to Gastrin (AS1A17)

Anti-Gastrin antibody

STJ93222 200 µl
EUR 197
Description: Rabbit polyclonal to Gastrin.

anti- Gastrin antibody

FNab03355 100µg
EUR 585
Description: Antibody raised against Gastrin

Anti-Gastrin antibody

PAab03355 100 ug
EUR 412

Anti-Cytokeratin 17 Rabbit Monoclonal Antibody

M02289-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cytokeratin 17 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Cytokeratin 17

DB-101-1 1 ml
EUR 518
Description: rabbit monospecific clonal antibodies for ihc-p application; concentrated

Gastrin I (human)

B5358-1 1 mg
EUR 363

Gastrin I (1-14) (human)

SP-100258-1 1 mg
EUR 164

miRZip-17 anti-miR-17 microRNA construct

MZIP17-AA-1 Miniprep DNA
EUR 684

miRZip-17 anti-miR-17 microRNA construct

MZIP17-PA-1 Bacterial Streak
EUR 684

Gastrin 17 Antigen (HM682 or HM683)

VAng-Cr3883-1mg 1 mg
EUR 1686
Description: Gastrin 17 Antigen, Host/Source: Synthetic. Matched Pair: HM682 or HM683.

Gastrin I (rat)

SP-100259-1 1 mg
EUR 164

17-Hydroxyprogesterone (17-OHP) ELISA Kit

DLR-17-OHP-Ge-48T 48T
EUR 469
Description: A competitive inhibition quantitative ELISA assay kit for detection of 17-Hydroxyprogesterone (17-OHP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

17-Hydroxyprogesterone (17-OHP) ELISA Kit

DLR-17-OHP-Ge-96T 96T
EUR 608
Description: A competitive inhibition quantitative ELISA assay kit for detection of 17-Hydroxyprogesterone (17-OHP) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Rabbit Anti Gastrin Polyclonal Antibody

CPBT-65757RG 50 µl*
EUR 767

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit

RD-17-OHP-Ge-48Tests 48 Tests
EUR 467

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit

RD-17-OHP-Ge-96Tests 96 Tests
EUR 646

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit

RDR-17-OHP-Ge-48Tests 48 Tests
EUR 488

General 17-Hydroxyprogesterone (17-OHP) ELISA Kit

RDR-17-OHP-Ge-96Tests 96 Tests
EUR 676

Gastrin Releasing Peptide (GRP) (1-16) (porcine)

SP-100261-1 1 mg
EUR 164

[Leu15]-Gastrin I (human)

SP-100257-1 1 mg
EUR 225

17?-Hydroxywortmannin

B2095-1
EUR 142

17-AAG

1774-1
EUR 202

Gastrin Antibody

33384-100ul 100ul
EUR 252

Gastrin Antibody

33384-50ul 50ul
EUR 187

Gastrin Antibody

AF5352 200ul
EUR 304
Description: Gastrin Antibody detects endogenous levels of total Gastrin.

Gastrin Antibody

ABF0593 100 ug
EUR 438

Gastrin Antibody

ABF5352 100 ug
EUR 438

Gastrin antibody

20-GR03 1 ml
EUR 273
Description: Rabbit polyclonal Gastrin antibody

Gastrin Antibody

AF0593 200ul
EUR 304
Description: Gastrin Antibody detects endogenous levels of Gastrin.

Gastrin antibody

20R-2560 50 uL
EUR 532
Description: Guinea Pig polyclonal Gastrin antibody

Gastrin antibody

70R-31204 100 ug
EUR 327
Description: Rabbit polyclonal Gastrin antibody

Gastrin antibody

70R-49765 100 ul
EUR 244
Description: Purified Polyclonal Gastrin antibody

Gastrin antibody

20R-GR002 250 uL
EUR 539
Description: Rabbit polyclonal Gastrin antibody

YAP-TEAD Inhibitor 1 (Peptide 17)

A1149-1 1 mg
EUR 235

Gastrin-1, human

HY-P1097 1mg
EUR 199

Gastrin-1, human

5-01193 4 x 1mg Ask for price

Gastrin-1, rat

5-01194 4 x 1mg Ask for price

Gastrin-1 Peptide

20-abx265560
  • EUR 314.00
  • EUR 425.00
  • EUR 620.00
  • 0.5 mg
  • 1 mg
  • 2.5 mg

IL-17 Interleukin-17 Human Recombinant Protein

PROTQ16552-1 Regular: 25ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

Anti-Monomethyl-Histone H3 (Lys9) Rabbit Monoclonal Antibody, Clone#RM150

M06819-17 100ug
EUR 479
Description: Anti-Monomethyl-Histone H3 (Lys9) Rabbit Monoclonal Antibody, Clone#RM150 tested in WB, ELISA, Multiplex, ChIP, ICC, reactive to All Vertebrates

Biotin-[Gln1]-Gastrin I (human)

SP-100255-1 1 mg
EUR 225

OXA (17-33)

B5808-1 1 mg
EUR 561

EZSolution? 17-AAG

9495-1
EUR 202

17-DMAG hydrochloride

1776-1
EUR 191

Anti-Keratin 17 antibody

STJ16100289 1 mL
EUR 534

Anti-Cytokeratin 17 antibody

STJ16100350 1 mL
EUR 1464

Anti-Keratin 17 antibody

STJ16101023 100 µg
EUR 354

Anti-Cadherin-17 antibody

STJ180027 0.1 ml
EUR 212

Anti-Cytokeratin 17 antibody

STJ180141 0.1 ml
EUR 212

Anti-CK-17 antibody

STJ190032 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CK-17 (5C1)

Anti-FGF-17 Antibody

A07009 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for FGF-17 Antibody (FGF17) detection.tested for IHC, WB in Human.

Anti-Keratin 17 Antibody

A02289 100ul
EUR 397
Description: Rabbit Polyclonal Keratin 17 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Sox-17 antibody

STJ96420 200 µl
EUR 197
Description: Rabbit polyclonal to Sox-17.

Anti-Claudin-17 antibody

STJ96501 200 µl
EUR 197
Description: Rabbit polyclonal to Claudin-17.

Anti-FGF-17 antibody

STJ97249 200 µl
EUR 197
Description: Rabbit polyclonal to FGF-17.

Anti-Cytokeratin 17 antibody

STJ97983 100 µl
EUR 234
Description: Mouse monoclonal to Cytokeratin 17.

Anti-ADAMTS-17 antibody

STJ91480 200 µl
EUR 197
Description: Rabbit polyclonal to ADAMTS-17.

Anti-CPI-17 antibody

STJ92448 200 µl
EUR 197
Description: Rabbit polyclonal to CPI-17.

Anti-Cytokeratin 17 antibody

STJ92630 200 µl
EUR 197
Description: Rabbit polyclonal to Cytokeratin 17.

Anti-HMG-17 antibody

STJ93550 200 µl
EUR 197
Description: Rabbit polyclonal to HMG-17.

Anti-HMG-17 antibody

STJ93551 200 µl
EUR 197
Description: Rabbit polyclonal to HMG-17.

anti- Cytokeratin 17 antibody

FNab02201 100µg
EUR 505.25
Description: Antibody raised against Cytokeratin 17

anti- Cytokeratin 17 antibody

FNab02202 100µg
EUR 585
Description: Antibody raised against Cytokeratin 17

anti- IL-17 antibody

FNab04224 100µg
EUR 548.75
Description: Antibody raised against IL-17

anti- IL-17 antibody

FNab04225 100µg
EUR 505.25
Description: Antibody raised against IL-17

anti- Syntaxin 17 antibody

FNab08448 100µg
EUR 548.75
Description: Antibody raised against Syntaxin 17

Anti-Cytokeratin 17 antibody

PAab02201 100 ug
EUR 355

Anti-Cytokeratin 17 antibody

PAab02202 100 ug
EUR 412

Anti-IL-17 antibody

PAab04224 100 ug
EUR 386

Anti-Syntaxin 17 antibody

PAab08448 100 ug
EUR 386

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody

A00138-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-PAI-1 Antibody

A00637-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

Anti-Flk-1 Antibody

A00901-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-EDG-1 Antibody

A01502-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody

A01530-1 100ug
EUR 455
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody

A03761-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody

A03828-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody

A05494-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Periphilin 1 Antibody

A06996-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody

A07491-1 100ul
EUR 397
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Anti-GLI-1 Antibody

A07972-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for GLI-1 Antibody (ACSS1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Cerebellin 1 Antibody

A09176-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cerebellin 1 Antibody (CBLN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-DOC-1 Antibody

A09467-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DOC-1 Antibody (CDK2AP1) detection. Tested with WB in Human, Mouse.

Anti-Bag-1 Antibody

A02423-1 50 ul
EUR 397
Description: Rabbit Polyclonal Bag-1 Antibody. Validated in IP, IHC and tested in Bovine, Canine, Human, Mouse, Rat.

Anti-TUB 1 Antibody

A02917-1 100ug/vial
EUR 294

Anti-Dok-1 Antibody

A03039-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dok-1 Antibody (DOK1) detection.tested for WB in Human, Mouse, Rat.

Anti-NPDC-1 Antibody

A12846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for NPDC-1 Antibody (NPDC1) detection. Tested with WB in Human, Mouse, Rat.

Gastrin

RA20055 100 ul
EUR 370

Gastrin

RA21016 50 ug
EUR 344

Boc-(Asp(OBzl)16)-Gastrin I (13-17) (human)

A-4310.0025 25.0mg
EUR 212
Description: Sum Formula: C43H53N7O9S; CAS# [78700-57-9]

Boc-(Asp(OBzl)16)-Gastrin I (13-17) (human)

A-4310.0100 100.0mg
EUR 576
Description: Sum Formula: C43H53N7O9S; CAS# [78700-57-9]

Boc-(Asp(OBzl)16)-Gastrin I (13-17) (human)

5-00833 4 x 5mg Ask for price

Boc-(Asp(OBzl)16)-Gastrin I (13-17) Peptide

20-abx265312
  • EUR 384.00
  • EUR 565.00
  • EUR 300.00
  • 10 mg
  • 25 mg
  • 5 mg

Anti-Gastrin Releasing Peptide (3A11)

YF-MA13342 100 ug
EUR 363
Description: Mouse monoclonal to Gastrin Releasing Peptide

FT3 (Free triiodothyronine) ELISA test

17 96T/Box Ask for price
Description: ELISA based test for quantitative detection of FT3 (Free triiodothyronine)

Biotin-[Glu1]-Gastrin I (human) (phosphorylated)

SP-100256-1 1 mg
EUR 225

Gastrin Polyclonal Antibody

ES5410-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against Gastrin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Gastrin Polyclonal Antibody

ES5410-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against Gastrin from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

Human Gastrin Antibody

10901-05011 150 ug
EUR 217

Gastrin (GT) Antibody

20-abx131060
  • EUR 453.00
  • EUR 133.00
  • EUR 1302.00
  • EUR 620.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GAST) Antibody

20-abx123470
  • EUR 411.00
  • EUR 592.00
  • 100 ul
  • 200 ul

Gastrin Polyclonal Antibody

ABP54411-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of Gastrin from Human, Mouse, Rat. This Gastrin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Gastrin at AA rangle: 30-110

Gastrin Polyclonal Antibody

ABP54411-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of Gastrin from Human, Mouse, Rat. This Gastrin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Gastrin at AA rangle: 30-110

Gastrin Polyclonal Antibody

ABP54411-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of Gastrin from Human, Mouse, Rat. This Gastrin antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human Gastrin at AA rangle: 30-110

Gastrin (GT) Antibody

20-abx100041
  • EUR 439.00
  • EUR 133.00
  • EUR 1247.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GT) Antibody

20-abx100042
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GT) Antibody

20-abx100043
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GAST) Antibody

20-abx009245
  • EUR 300.00
  • EUR 439.00
  • EUR 189.00
  • 100 ul
  • 200 ul
  • 30 ul

Gastrin (GAST) Antibody

20-abx013089
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

Gastrin (GAST) Antibody

abx025414-100ul 100 ul
EUR 523

Gastrin (GAST) Antibody

abx233355-100ug 100 ug
EUR 551

Gastrin (GT) Antibody

20-abx176568
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GT) Antibody

20-abx176569
  • EUR 411.00
  • EUR 133.00
  • EUR 1149.00
  • EUR 565.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Gastrin (GT) Antibody

20-abx176570
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug

Gastrin (GT) Antibody

20-abx176571
  • EUR 1302.00
  • EUR 620.00
  • 1 mg
  • 200 ug

Gastrin (GT) Antibody

20-abx172525
  • EUR 815.00
  • EUR 425.00
  • 1 mg
  • 200 ug

Gastrin (GT) Antibody

20-abx172526
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug

Gastrin (GT) Antibody

20-abx172527
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Gastrin (GT) Antibody

20-abx172528
  • EUR 913.00
  • EUR 467.00
  • 1 mg
  • 200 ug

Gastrin (GAST) Antibody

20-abx329269
  • EUR 314.00
  • EUR 244.00
  • 100 ug
  • 50 ug

Gastrin (GAST) Antibody

abx331567-100ul 100 ul
EUR 425

Gastrin Conjugated Antibody

C33384 100ul
EUR 397

Gastrin/CCK antagonist 1

HY-U00375 10mg
EUR 9417

Big Gastrin - 1, human

5-00768 4 x 1mg Ask for price

Apelin-17 (human, bovine)

B5359-1 1 mg
EUR 447

Anti-Esrp-1 Monoclonal Antibody

M06068-1 100uL
EUR 443
Description: Mouse Monoclonal Esrp-1 Antibody. Validated in WB and tested in Human.

Anti-Presenilin 1 Monoclonal Antibody

M00138-1 100ug
EUR 397
Description: Rabbit Monoclonal Presenilin 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Anti-Galectin 1 Monoclonal Antibody

M00470-1 100ug
EUR 397
Description: Rabbit Monoclonal Galectin 1 Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-DJ-1 Monoclonal Antibody

M00757-1 100ul
EUR 397
Description: Mouse Monoclonal DJ-1 Antibody. Validated in IHC, WB and tested in Bovine, Human.

Anti-Enolase 1 Monoclonal Antibody

M01250-1 100ul
EUR 397
Description: Anti-Enolase 1 Monoclonal Antibody tested in WB, IF, ICC, IHC, reactive to Human, rat, mouse, cow, pig, horse

Anti-Dynamin 1 Monoclonal Antibody

M02536-1 100ug
EUR 397
Description: Rabbit Monoclonal Dynamin 1 Antibody. Validated in IF, WB and tested in Human, Mouse, Rat.

Anti-Angiopoietin 1/ANGPT1 Antibody

PA1333-1 100ug/vial
EUR 334

Anti-Galectin 1/LGALS1 Antibody

PB9240-1 100ug/vial
EUR 334

Anti-TNF Receptor 1 Antibody

A00294-1 200ug
EUR 522
Description: Rabbit Polyclonal TNF Receptor 1 Antibody. Validated in IP, IHC, WB and tested in Human, Mouse, Rat.

Anti-Galectin 1/Lgals1 Antibody

A00470-1 100ug/vial
EUR 334

Anti-LOX-1/OLR1 Antibody

A00760-1 100ug/vial
EUR 294

Anti-Syndecan-1/SDC1 Antibody

A00991-1 100ug/vial
EUR 294

Anti-IRAK-1/IRAK1 Antibody

A01021-1 100ug/vial
EUR 334

Anti-Neurexin 1/NRXN1 Antibody

A01490-1 100ug/vial
EUR 334

Anti-Hexokinase 1/HK1 Antibody

A01504-1 100ug/vial
EUR 334

Anti-Musashi 1/Msi1 Antibody

A05052-1 100ug/vial
EUR 334

Anti-Pyrophosphatase 1/PPA1 Antibody

A07485-1 100ug/vial
EUR 334

Anti-TCP-1 eta Antibody

A08169-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 eta Antibody (CCT7) detection. Tested with WB in Human, Mouse, Rat.

Anti-Relaxin 1/RLN1 Antibody

A08367-1 100ug/vial
EUR 334

Anti-TCP-1 zeta Antibody

A09373-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TCP-1 zeta Antibody (CCT6A) detection.tested for WB in Human, Mouse, Rat.

Anti-Synaptotagmin 1/SYT1 Antibody

A02314-1 100ug/vial
EUR 334

Anti-Syntenin-1 Monoclonal Antibody

A02475-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for Syntenin-1 Antibody (SDCBP) detection. Tested with WB in Human, Rat, Dog, Pig.

Anti-Dsg1/Desmoglein 1 Antibody

A02655-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Dsg1 Antibody (DSG1) detection.tested for IHC, WB in Human, Mouse, Rat.

Anti-CAF-1 p150 Antibody

A02732-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CAF-1 p150 Antibody (CHAF1A) detection. Tested with WB in Human, Mouse.

Anti-Talin 1/TLN1 Antibody

A02859-1 100ug/vial
EUR 334

Anti-Islet 1/ISL1 Antibody

A02969-1 100ug/vial
EUR 334

Anti-CHST8/Galnac4St 1 Antibody

A10989-1 100ul
EUR 397
Description: Rabbit Polyclonal CHST8/Galnac4St 1 Antibody. Validated in WB and tested in Human, Mouse, Rat.

Mouse pre-microRNA Expression Construct mir-17+18a+19a+20a+19b-1+92a-1

MMIR-17-92a-PA-CL Bacterial Streak
EUR 968

THP-1 Cell Slide

17-008 1 pack
EUR 180.5
Description: THP-1 (monocyte; acute monocytic leukemia)

Anti-Cytokeratin 17

DB101RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 17

DB101RTU-7 7 ml
EUR 200
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

We show that the variants identified IKZF1 (p.His195Arg) alter histidine residues absolutely conserved required for folding of the three zinc-finger protein IKAROS, lead to the loss of the characteristics of nuclear immunofluorescence staining pattern. In our case, genetic testing is essential for diagnosis IKAROS haploinsufficiency, the presentation of which are known, including infections, aberrant hematopoiesis, leukemia, and age-related decline in humoral immunity. Our family studies underscore that, after infection, ITP is the most common clinical manifestation of both IKAROS haploinsufficiency.